The major active component of the Verebey Joint Support is NIACIN. NIACIN AND NIACINAMIDE are precursors of the biochemical cofactors NAD+ and NADH. (NAD = Nicotinamide dinucleotide). These biochemical cofactors are involved in a large number of critical biochemical reactions. They function in all living cells in the body.
NIACIN is converted in the body to NIACINAMIDE which is further converted into NAD+ and NADH .These critical electron transferor cofactors are involved in energy, lipid, and protein synthesis and catabolism. They are involved in the overall metabolic activity of the body.
NIACIN and NIACINAMIDE are highly water soluble and rapidly excreted from the body. Yet high bioavailability is necessary for youthful cellular and tissue functions. Dr. Ying’s known publication suggests that DEFICIENCY of NAD+ and NADH Cofactors in the body are responsible for aging and age related diseases. (Ying W, NAD+ and NADH in cellular functions and cell death, 2006, Frontiers in Bioscience, 11:3129-3148)
The exact mechanism directly showing niacin’s ability reducing inflammation related pain and supporting rebuilding joints is not known. However, clinical observations of increased joint flexibility and specific measurements of blood erythrocyte sedimentation rate (ESR) improvements prove niacinamide’s effectiveness in the treatment of joint diseases.
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